Brian Nolan, 69, had just planned a memorial for his sister who died in January after her 20-year battle with cancer before receiving the news.
Tragically, grieving Brian was then diagnosed with cancer himself three days later.
“I just want cancer to leave us alone,” Brian told the Mirror, the fifth of the eight Nolan siblings.
He added: “You’re never ready for somebody to say: ‘Yes, you’ve got cancer’.
"It’s like being hit by a train. You start plunging into the abyss of: ‘I’m going to die’."
His Loose Women host sister Coleen "couldn't speak" when he broke the news saying that he went completely numb before wanting to punch walls and scream.
The Nolan family is heartbreakingly no stranger to cancer, losing Bernie to breast cancer in 2013 aged 52, before Linda, 65, earlier this year.
Anne, 74, was diagnosed with breast cancer in 2000 and Coleen, 60, learned she had skin cancer in 2023.
Now Brian must undergo treatment to tackle his level two prostate cancer - which thankfully has not spread to the rest of his body.
The urologist assured him that they were going to cure his cancer and he said he hopes he can have the courage his sisters had.
He will soon undergo surgery to remove his prostate gland during his battle with the disease.
Coleen Nolan chokes back tears as she admits nearly quitting Loose Women after sister Linda's death
Brian first noticed something was wrong after needing to use the toilet more frequently than usual.
After a trip to the GP where doctors carried out PSA tests, an MRI, and a biopsy, it was revealed he had the disease.
Losing Linda was tough for Brian and he said the pain left him struggling to sleep.
The loving brother chose not to tell Linda the his growing cancer fears, who passed away on January 15.
He said he was able to do this with the support of his wife Anne to protect his siblings who were already distraught by Linda's death.
She died after a battle with secondary breast cancer, aged 65, with her famous sisters at her side.
Her final hours were said to have been full of "love and comfort."
How the Nolan Sisters bravely fought ‘cancer curse’
The Nolan Sisters know better than anyone how devastating cancer can be with the family bravely battling against the "cursed" disease multiple times.
Last year, it was revealed that Loose Women presenter Coleen had been diagnosed with basal cell carcinoma on her shoulder and melanoma on her face.
Their father, Tommy Nolan Sr, was the first to be struck by the cruel disease, with him dying from cancer in 1998.
Anne was the first sister to be diagnosed with breast cancer in 2000.
The star was then diagnosed with stage three breast cancer 20 years later in April 2020 and is now in remission after receiving the all-clear.
Just days after her second diagnosis, her younger sister Linda found out about her liver cancer - a cancer that their father died from.
This came after Linda was first diagnosed with breast cancer in 2005.
While she underwent gruelling treatment, her beloved husband Brian Hudson died from skin cancer aged just 60.
Meanwhile, their late sister Bernie announced she had been diagnosed with breast cancer in April 2010.
The star passed at her home in Surrey in July 2013 aged just 52.
Linda passed tragically away January 15, aged 65, just weeks after Brian's prostate cancer diagnosis.
What is prostate cancer?
Prostate cancer affects a small, walnut shaped gland that sits underneath the bladder and surrounds the urethra - the tube carrying pee outside the body.
It usually grows bigger as you get older.
The prostate's main job is to help make semen – the fluid that carries sperm.
Most men with early prostate cancer don’t have any signs or symptoms - that’s why it’s important to know about your risk.
If you do notice changes in the way you urinate, this is more likely to be a sign of an enlarged prostate, which is very common and non-cancerous.
But it’s still a good idea to get it checked out.
In the UK, about one in eight men will be diagnosed with prostate cancer in their lifetime.
Some factors may mean you're more likely to get it.
If you have any of these risk factors or if you have any symptoms, speak to your GP.
They can talk to you about your risk, and about the tests that are used to diagnose prostate cancer.